This calculator shows how much points you need to reach certain layer, works for both prestige and ascension
Only works for layers in which you have zero points and zero stats upgrades (gameplay unlocks are fine)
Put layer you want to start calculating with in "Current Layer",
Layer you want to unlock in "Target Layer",
Amount of points you want in target layer in "Target Points".

Shift-click on buttons to add/subtract 10

Amount of ascension points gained depends on your highest layer, highest level and current amount of points including ones spent on the stats upgrade.
Highest level you can reach per layer may vary, so those combinations were extrapolated on available data (PL20 to PL30 test runs).
Combinations of layer/level you can reach may slightly differ.
But considering those selected, ascension point gain calculation is accurate.

Fill your current ascension unspent points and exp upgrades below (0 if you have none)

Shift-click on buttons to add/subtract 10

Ascension stats

Shift-click on buttons to add/subtract 10